ICMJE Registration Requirements
International Committee for Medical Journal Editors
What is ICMJE?
The ICMJE is a group of general medical journal editors that include:
- New England Journal of Medicine
- Journal of the American Medical Association
- Annals of Internal Medicine
- The Lancet
- The Medical Journal of Australia
- The New Zealand Medical Journal
- Norwegian Medical Journal
- Canadian Medical Association Journal
- Croatian Medical Journal
- Dutch Journal of Medicine
- Journal of the Danish Medical Association
What are the ICMJE requirements for clinical trials registration?
The ICMJE member journals will require, as a condition of consideration for publication in their journals, registration in a public trials registry.
The ICMJE defines a clinical trial as any research project that prospectively assigns human subjects to intervention or concurrent comparison or control groups to study the cause-and-effect relationship between a medical intervention and a health outcome. Medical interventions include drugs, surgical procedures, devices, behavioral treatments, process-of-care changes, and the like.
More information can be found at:
ICMJE Obligation to Register Clinical Trials
When do I register?
Registration must be completed:
- Prior to enrollment of 1st subject, AND
- Updated at least every 6 months